Generic Zyban Bupropion 150mg BUPROPION (Zyban) is used for treating depression. Bupropion is an antidepressant. It works in the brain to treat depression. Exactly how it works is not known.

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What are bupropion tablets?

BUPROPION (Wellbutrin®) belongs to a family of drugs known as "antidepressants", a medicine that helps to lift mental depression. Bupropion acts differently from other antidepressants and may be useful for treating patients who have had unusual or limiting effects from other antidepressants.

What medicines may interact with Zyban?

NOTE: Do not take Zyban with other medicines containing bupropion, like Zyban®.

Other medicines that can interact with Zyban include:

• alcohol
• medicines for mental depression, emotional, or psychotic disturbances
• carbamazepine
• doxercalciferol
• cocaine
• rifampin
• dextroamphetamine
• kava kava, Piper methysticum
• amphetamine
• levodopa or combination drugs containing levodopa
• cimetidine
• medications or herbal products for weight control or appetite
• corticosteroids
• medicines for difficulty sleeping
• medicines called MAO inhibitors-phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), and selegiline (Eldepryl®)
• nicotine
• tramadol
• phenobarbital
• phenytoin
• some medicines for pain, such as codeine
• ritonavir
• valproic acid
• some medicines for migraine headache (propranolol)
• orphenadrine
• St. John's wort, Hypericum perforatum
• theophylline
• some medicines for heart rhythm or blood pressure
• valerian, Valeriana officinalis
• linezolid
• warfarin

Tell your doctor about all other medicines you are taking, including unprescripted medicines,herbal products ,or nutritional supplements . Also tell your doctor if you frequently take drinks with caffeine or alcohol,or if you smoke. These may affect the way Zyban works. Check with your health care professional before stopping or starting any of your medicines.

What should my doctor be informed about before I take Zyban?

He needs to know whether you feel any of these conditions:

• frequently drink alcoholic beverages
• an eating disorder, such as anorexia or bulimia
• Tourette's syndrome
• heart disease, previous heart attack, or irregular heart beat
• an unusual or allergic reaction to bupropion, other medicines, foods, dyes, or preservatives
• high blood pressure
• pregnant or trying to become pregnant
• liver disease
• bipolar disorder or psychosis
• seizures (convulsions)
• suicidal thoughts or a previous suicide attempt
• head injury or brain tumor
• weight loss
• kidney disease
• breast-feeding
• use of sedatives

How should Zyban be taken?

Take pills by mouth.Precisely follow the directions on the prescription form. Zyban can be taken with or without food. If it upsets your stomach it may help to take it a glass of warm water or milk. Take your doses according to your daily schedule. Do not take it more often than prescribed. Finish the full course prescribed by your doctor even if you think your condition gets better. Do not stop taking except your doctor say otherwise.

Contact your doctor concerning the use of this medicine by children. Special care may be needed.

If you miss a dose...

Take the forgotten dose as soon as you recollect. However, if it is almost time for your next dose, skip the one you missed and keep your regular schedule. Never try to "catch up" by doubling the dose!

What side effects may I feel during Zyban treatment?

Side effects that should immediately be reported to your prescriber or health care professional:

Uncommon:

• blurred vision
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• hallucinations
• increased blood pressure
• difficulty breathing or wheezing
• fast or irregular heartbeat (palpitations)
• unusual tiredness or weakness

More common:

• agitation, anxiety, or restlessness, especially in the first week of treatment or when doses are changed
• skin rash, itching, hives
• seizures
• confusion
• vomiting

Side effects that do not require special medical attention (visit your doctor if they continue or are bothersome):

Less common:

• menstrual changes
• loss of sexual drive
• loss of appetite

More common:

• change in taste
• increased sweating
• difficulty sleeping
• tremor
• dry mouth
• constipation
• headache
• dizziness
• nausea
• weight loss

What should I take into consideration during Zyban treatment?

Visit your doctor for regular checks on your progress. You may have to take bupropion for several days before you see the effects. Your prescriber or health care professional may want you to gradually reduce the dose; ask for advice.

Patients and their families should watch out for worsening depression or thoughts of suicide. Also watch out for sudden or severe changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of bupropion treatment or after a change in dose, call your doctor.

Do not treat yourself for coughs, colds, or allergies without asking your prescriber or health care professional for advice. Also do not take any herbal or non-prescription medicines for weight loss without your prescribers advice. Some ingredients may increase possible side effects.

Tell your doctor or dentist that you take Zyban before you receive any medical or dental care, emergency care, or surgery.